I especially like how the backgrounds on the profile pages work, as I've expressed in another thread already. It maintains the nice intuitive feel of the other Whiskey sites, while still being different. Great stuff so far, I'm really excited for this site.
I'm on the fence. It seems like it was rushed a bit, which I believe Dave Snider has admitted that it was, so hopefully there'll be a bit of a design update in the future. Oddly enough it seems a little plain to me when it does in fact use more colors and quirks than all three of the other Whiskey sites. Weird.
Vertical constraints. So there is a gray box around everything. When you pick a tab, its like a file folder. I hate that.
I have a widescreen monitor and it never renders nicely ie it looks stretched out. if you look at engadget, they take away the need for constraining their content by making the background a solid color and centering the text.
I can only look at the site for about 5-10 minutes before I started feeling blinded and need to switch back to GB.
Also, the main page seems a bit cluttered at the moment. It's like if, instead of GB having thumbnail links to their new articles and videos, they just threw it all up one after the other on the main page.