I'm no audiophile, so I don't have anything too fancy.
Home Theater: Yamaha HTR-5630
5.1 receiver with Athena ASC-1 center, Sony SS-MB215 front, Sony SS-MB115 rear, Polk Audio PSW404 sub. Save for the subwoofer, they're all entry level stuff, but I think they sound great. I'm planning on "downgrading" my speakers to satellites in a few months. Big speakers seemed like a good idea back when I bought them, but I've decided they're
too big.
Computer: Harman/Kardon Soundsticks II 2.1 system. I got some cheap Harman/Kardon speakers with my computer a long time ago and they sounded great for the price, so I went with the same brand. I think their defining feature is that they look crazy, but they sound great nonetheless. Only complaint I have is that the power button is on the back of the subwoofer, so whenever I want to turn them on I have to bend down and reach for the switch. If I had known about the power button being in such a stupid place beforehand I probably wouldn't have bought them, but it doesn't bother me enough to go out and get another system.